Madras et al (2006) in a very modern paper shown in vivo binding of modafinil to striatal DAT and thalamic NET in rhesus monkeys employing PET imaging. The investigators in comparison binding with the DAT probe [11C]CFT and also the Web probe [11C]MeNER from the absence of modafinil with the binding of those probes during the presence of modafinil

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